Effect of acetaldehyde on hepatic microsomal drug-metabolizing enzyme activities in vitro

Sex difference in the activities of microsomal drug-metabolizing enzyme systems in relation to dietary protein.

‰Á " ¡ —²ˆê Kato et al. (1-3) and Booth and Gillette (4) demonstrated that the sex difference in the activities of drug-metabolizing enzyme systems of rat liver microsomes is related to the anabolic action of male sex hormone. In fact, they demonstrated increases in the activities of drug-metabolizing enzymes of liver microsomes of castrated female rats by the treatment with synthetic hormones ...

the effect of e-64 on the developmental competence of sheep cocs during in vitro maturation

in the present study, the effect of e-64 at different concentrations (0.5, 1, 5 and 10 µm) added to (1) the ivm medium on oocyte nuclear maturation and developmental competence of ovine oocytes, and (2) to the ivc medium on embryonic development of ovine embryos were investigated.

Hormonal regulation of hepatic drug-metabolizing enzyme activity during adolescence.

Activities of drug-metabolizing enzymes (DMEs) are known to change throughout the course of physical and sexual maturation, with the greatest variability noted during infancy and adolescence. The mechanisms responsible for developmental regulation of DME are currently unknown. However, the hormonal changes associated with puberty/adolescence provide a theoretical framework for understanding the...

Effects of butyrate on hepatic epigenetics and microsomal drug-metabolizing enzymes in chicken

Effect of administration of 3-aminotriazole on the activity of microsomal drug-metabolizing enzyme systems of rat liver.

protein pigment of microsomes and probably have an important role for the oxidation of drugs (4-10). Recently, Granick and Urata demonstrated that the administration of many drugs, including phenobarbital, markedly increased the activities of 6-amino levu Ionic acid synthetase and synthesis of porphyrine (11, 12). These results suggested that the increase in the activities of drug-metabolizing ...